Guido Verhoeven

<i>De novo</i> Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation

Evelien Rysman, Koen Brusselmans, Katryn Scheys et al. · Cancer Research · 2010 · 716 citations · Full text

Life Sciences, Biochemistry, Oncology +12

Induction of Cancer Cell Apoptosis by Flavonoids Is Associated with Their Ability to Inhibit Fatty Acid Synthase Activity

Koen Brusselmans, Ruth Vrolix, Guido Verhoeven et al. · Journal of Biological Chemistry · 2004 · 468 citations · Full text

Medicine, Oncology, Pharmacology +17

Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer

Johannes V. Swinnen, Tania Roskams, Steven Joniau et al. · International Journal of Cancer · 2001 · 376 citations

Medicine, Oncology, Pathology +17

Chemical Inhibition of Acetyl-CoA Carboxylase Induces Growth Arrest and Cytotoxicity Selectively in Cancer Cells

Annelies Beckers, Sophie Organe, Leen Timmermans et al. · Cancer Research · 2007 · 316 citations

Life Sciences, Oncology, Pharmacology +17

RNA interference-mediated silencing of the fatty acid synthase gene attenuates growth and induces morphological changes and apoptosis of LNCaP prostate cancer cells.

Ellen De Schrijver, Koen Brusselmans, Walter Heyns et al. · PubMed · 2003 · 271 citations

Life Sciences, Molecular Biology, Oncology +14