Tine Van de Sande

Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains

Johannes V. Swinnen, Paul P. Van Veldhoven, Leen Timmermans et al. · Biochemical and Biophysical Research Communications · 2003 · 253 citations

Biosynthesis, Engineering, Membrane Formation +10

Role of the phosphatidylinositol 3'-kinase/PTEN/Akt kinase pathway in the overexpression of fatty acid synthase in LNCaP prostate cancer cells.

Tine Van de Sande, Ellen De Schrijver, Walter Heyns et al. · PubMed · 2002 · 210 citations

Fatty Acid Synthase, Tumor Biology, Signaling Pathway +16

High‐level expression of fatty acid synthase in human prostate cancer tissues is linked to activation and nuclear localization of Akt/PKB

Tine Van de Sande, Tania Roskams, Evelyne Lerut et al. · The Journal of Pathology · 2005 · 134 citations

Mimicry of a Cellular Low Energy Status Blocks Tumor Cell Anabolism and Suppresses the Malignant Phenotype

Johannes V. Swinnen, Annelies Beckers, Koen Brusselmans et al. · Cancer Research · 2005 · 129 citations · Full text

Squalene Synthase, a Determinant of Raft-associated Cholesterol and Modulator of Cancer Cell Proliferation

Koen Brusselmans, Leen Timmermans, Tine Van de Sande et al. · Journal of Biological Chemistry · 2007 · 112 citations · Full text

Cancer Cell Proliferation, Oxysterol, Biochemistry +13