Concepedia

Agnes Leffler

AL

6

Publications

189

Citations

6

H-Index

2006

Active since

Affiliations

AstraZeneca (Sweden)(Current)

Agnes Leffler is an author at AstraZeneca (Sweden) specializing in medicine, molecular pharmacology, and pharmacology.

Top concepts

MedicinePharmacologyMolecular PharmacologyImmunologyPharmacotherapyCell SignalingBiochemistryDrug DiscoveryPeptide ScienceSmall Molecules

Publications per year

2006–2021

6

Publications

6

Benzoxazepines Achieve Potent Suppression of IL‐17 Release in Human T‐Helper 17 (T<sub>H</sub>17) Cells through an Induced‐Fit Binding Mode to the Nuclear Receptor RORγ

Roine I. Olsson, Yafeng Xue, Stefan von Berg et al. · ChemMedChem · 2015 · 61 citations

Characterization of species-related differences in the pharmacology of tachykinin NK receptors 1, 2 and 3

Agnes Leffler, Ingela Ahlstedt, Susanna Engberg et al. · Biochemical Pharmacology · 2009 · 38 citations · Full text

Molecular Pharmacology, Molecular Physiology, Functional Selectivity +9

Potent and Orally Bioavailable Inverse Agonists of RORγt Resulting from Structure-Based Design

Frank Narjes, Yafeng Xue, Stefan von Berg et al. · Journal of Medicinal Chemistry · 2018 · 37 citations · Full text

Drug Target, Retinoic Acid Receptor, Peptide Science +19

AZD0284, a Potent, Selective, and Orally Bioavailable Inverse Agonist of Retinoic Acid Receptor-Related Orphan Receptor C2

Frank Narjes, Antonio Llinàs, Stefan von Berg et al. · Journal of Medicinal Chemistry · 2021 · 24 citations · Full text

Molecular cloning, mutations and effects of NK1 receptor antagonists reveal the human-like pharmacology of gerbil NK1 receptors

Susanna Engberg, Ingela Ahlstedt, Agnes Leffler et al. · Biochemical Pharmacology · 2006 · 18 citations

Molecular Pharmacology, Nk1 Receptor Antagonists, G Protein-coupled Receptor +8

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