Genomic Instability Is Induced by Persistent Proliferation of Cells Undergoing Epithelial-to-Mesenchymal Transition

Valentine Comaills, Lilian Kabeche, Robert Morris, +20

Cell Reports

Hypoxia Increases Gefitinib-Resistant Lung Cancer Stem Cells through the Activation of Insulin-Like Growth Factor 1 Receptor

Akiko Murakami, Fumiyuki Takahashi, Fariz Nurwidya, +12

PLoS ONE

Dynamic Chromatin Modification Sustains Epithelial-Mesenchymal Transition following Inducible Expression of Snail-1

Sarah Javaid, Jianmin Zhang, Endre Anderssen, +11

Cell Reports

Homeobox B9 induces epithelial-to-mesenchymal transition-associated radioresistance by accelerating DNA damage responses

Naokazu Chiba, Valentine Comaills, Bunsyo Shiotani, +11

Proceedings of the National Academy of Sciences

SETD1A protects from senescence through regulation of the mitotic gene expression program

Ken Tajima, Satoru Matsuda, Toshifumi Yae, +14

Nature Communications

Hypoxia induces gefitinib resistance in non‐small‐cell lung cancer with both mutant and wild‐type epidermal growth factor receptors

Kunihiko Minakata, Fumiyuki Takahashi, Takeshi Nara, +10

Cancer Science

Inflammatory Lung DiseasePathologyGefitinib ResistanceCancer BiologyTumor Biology +16

Breast tumor progression induced by loss of BTG2 expression is inhibited by targeted therapy with the ErbB/HER inhibitor lapatinib

Fuminori Takahashi, Naokazu Chiba, Ken Tajima, +8

Oncogene

Breast OncologyBreast Tumor ProgressionMedicineBreast CancerCancer Biology +8

SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes

Ken Tajima, Toshifumi Yae, Sarah Javaid, +14

Nature Communications

Oct4 plays a crucial role in the maintenance of gefitinib-resistant lung cancer stem cells

Isao Kobayashi, Fumiyuki Takahashi, Fariz Nurwidya, +13

Biochemical and Biophysical Research Communications

MedicineCrucial RoleStem Cell ResearchCancer BiologyTumor Suppressor +6

Activation of insulin‐like growth factor‐1 receptor confers acquired resistance to osimertinib in non‐small cell lung cancer with <i>EGFR</i> T790M mutation

Daisuke Hayakawa, Fumiyuki Takahashi, Yoichiro Mitsuishi, +17

Thoracic Cancer