Scott McCauley

Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment

Vivian Barry-Hamilton, Rhyannon Spangler, Derek Marshall et al. · Nature Medicine · 2010 · 855 citations

Life Sciences, Biochemistry, Cell Biology +13

PEGylated IL-10 (Pegilodecakin) Induces Systemic Immune Activation, CD8+ T Cell Invigoration and Polyclonal T Cell Expansion in Cancer Patients

Aung Naing, Jeffrey R. Infante, Kyriakos P. Papadopoulos et al. · Cancer Cell · 2018 · 251 citations · Full text

Life Sciences, Immunology, Oncology +17

Selective Allosteric Inhibition of MMP9 Is Efficacious in Preclinical Models of Ulcerative Colitis and Colorectal Cancer

Derek Marshall, Susan K. Lyman, Scott McCauley et al. · PLoS ONE · 2015 · 195 citations · Full text

Medicine, Oncology, Pharmacology +17

Amyloid-β ¹¹ C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials

Enchi Liu, Mark E. Schmidt, Richard Margolin et al. · Neurology · 2015 · 152 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Modulation of Lysyl Oxidase-like 2 Enzymatic Activity by an Allosteric Antibody Inhibitor

Héctor M. Rodrı́guez, Maria Vaysberg, Amanda Mikels et al. · Journal of Biological Chemistry · 2010 · 136 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15