Héctor M. Rodrı́guez

Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment

Vivian Barry-Hamilton, Rhyannon Spangler, Derek Marshall et al. · Nature Medicine · 2010 · 841 citations

Redox Signaling, Allosteric Inhibition, Lysyl Oxidase–like-2 Impedes +7

A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice

Eric M. Green, Hiroko Wakimoto, Robert L. Anderson et al. · Science · 2016 · 691 citations · Full text

Cardiac Myosin Activation: A Potential Therapeutic Approach for Systolic Heart Failure

Fady I. Malik, James J. Hartman, Kathleen A. Elias et al. · Science · 2011 · 590 citations · Full text

Cardiac Muscle, Heart Failure, Cardiovascular Pharmacology +20

A small-molecule modulator of cardiac myosin acts on multiple stages of the myosin chemomechanical cycle

Raja Kawas, Robert L. Anderson, Sadie R Bartholomew Ingle et al. · Journal of Biological Chemistry · 2017 · 218 citations · Full text

Cardiac Muscle, Heart Failure, Engineering +16

Modulation of Lysyl Oxidase-like 2 Enzymatic Activity by an Allosteric Antibody Inhibitor

Héctor M. Rodrı́guez, Maria Vaysberg, Amanda Mikels et al. · Journal of Biological Chemistry · 2010 · 136 citations · Full text