Joshua T. Pearson

AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer

Michael J. Giffin, Keegan S. Cooke, Edward K. Lobenhofer et al. · Clinical Cancer Research · 2020 · 238 citations · Full text

Medicine, Oncology, Pharmacology +15

Targeting Multiple Myeloma with AMG 424, a Novel Anti-CD38/CD3 Bispecific T-cell–recruiting Antibody Optimized for Cytotoxicity and Cytokine Release

Christina L. Zuch de Zafra, Flordeliza Fajardo, Wendy Zhong et al. · Clinical Cancer Research · 2019 · 127 citations

Life Sciences, Immunology, Oncology +17

The kinetic mechanism for cytochrome P450 metabolism of Type II binding compounds: Evidence supporting direct reduction

Joshua T. Pearson, Upendra P. Dahal, Daniel Röck et al. · Archives of Biochemistry and Biophysics · 2011 · 31 citations · Full text

Medicine, Biochemistry, Pharmacology +13

Interleukin‐21 Receptor Blockade Inhibits Secondary Humoral Responses and Halts the Progression of Preestablished Disease in the (NZB × NZW)F1 Systemic Lupus Erythematosus Model

Ming Zhang, Gang Yu, Brian Chan et al. · Arthritis & Rheumatology · 2015 · 29 citations

Life Sciences, Immunology, Pathobiology +17