Jimmy Beckers

HDAC6 inhibition restores TDP‐43 pathology and axonal transport defects in human motor neurons with TARDBP mutations

Raheem Fazal, Steven Boeynaems, Ann Swijsen et al. · The EMBO Journal · 2021 · 106 citations · Full text

Life Sciences, Neurology, Neuroscience +17

<i>C9orf72</i> -derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility

Laura Fumagalli, Florence L. Young, Steven Boeynaems et al. · Science Advances · 2021 · 90 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition

Katarina Stoklund Dittlau, Emily N. Krasnow, Laura Fumagalli et al. · Stem Cell Reports · 2021 · 83 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

A toxic gain-of-function mechanism in C9orf72 ALS impairs the autophagy-lysosome pathway in neurons

Jimmy Beckers, Arun Kumar Tharkeshwar, Laura Fumagalli et al. · Acta Neuropathologica Communications · 2023 · 34 citations · Full text

Life Sciences, Neurology, Neuroscience +17

HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS

Elke Braems, Valérie Bercier, Evelien Van Schoor et al. · Acta Neuropathologica · 2022 · 25 citations · Full text

Life Sciences, Neurology, Neuroscience +17