Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans

Rayner Rodriguez‐Diaz, Robin Dando, Maria C. Jacques-Silva, +7

Nature Medicine

Non-neuronal Paracrine SignalMolecular PhysiologyNeurophysiologyPhysiologyNeurotransmitter +11

Human Beta Cells Produce and Release Serotonin to Inhibit Glucagon Secretion from Alpha Cells

Joana Almaça, Judith Molina, Danusa Menegaz, +5

Cell Reports

ATP-binding cassette A1 deficiency causes cardiolipin-driven mitochondrial dysfunction in podocytes

Gloria Michelle Ducasa, Alla Mitrofanova, Shamroop Kumar Mallela, +22

Journal of Clinical Investigation

Lipid PeroxidationCellular PhysiologyAbca1 ExpressionOxidative StressMetabolic Syndrome +16

Control of Insulin Secretion by Cholinergic Signaling in the Human Pancreatic Islet

Judith Molina, Rayner Rodriguez‐Diaz, Alberto Fachado, +3

Diabetes

Glucose HomeostasisInsulin SignalingGastrointestinal Peptide HormoneMolecular PharmacologyEffects Acetylcholine Produces +15

Noninvasive in vivo model demonstrating the effects of autonomic innervation on pancreatic islet function

Rayner Rodriguez‐Diaz, Stephan Speier, R. Damaris Molano, +11

Proceedings of the National Academy of Sciences

Pancreas TransplantationGlucose ToleranceOptogeneticsInsulin SignalingSocial Sciences +20

Donor Islet Endothelial Cells in Pancreatic Islet Revascularization

Daniel Nyqvist, Stephan Speier, Rayner Rodriguez‐Diaz, +14

Diabetes

Mechanism and effects of pulsatile GABA secretion from cytosolic pools in the human beta cell

Danusa Menegaz, D. Walker Hagan, Joana Almaça, +15

Nature Metabolism

Protein SecretionMolecular PhysiologySignal TransductionBiochemistryNatural Sciences +9

SMPDL3b modulates insulin receptor signaling in diabetic kidney disease

Alla Mitrofanova, Shamroop Kumar Mallela, Gloria Michelle Ducasa, +23

Nature Communications

Young capillary vessels rejuvenate aged pancreatic islets

Joana Almaça, Judith Molina, Rafael Arrojo e Drigo, +5

Proceedings of the National Academy of Sciences

InflammationGlucose SensingInsulin SignalingPancreatic IsletsAging +10

High-resolution, noninvasive longitudinal live imaging of immune responses

Midhat H. Abdulreda, Gaetano Faleo, R. Damaris Molano, +14

Proceedings of the National Academy of Sciences