Cell Reports · 2016 · 194 citations · 58 references
Life SciencesEndocrinologyPhysiologyCell SignalingMetabolic RegulationSignal TransductionDiabetes MellitusGlucose HomeostasisGlycemic ControlHormone SecretionPancreatic EndocrinologyPancreatic HormonesAutocrine HormonesIslet Cell PhysiologyPancreatic Hormone SecretionPancreatic Islet CellsPancreatic Islet PhysiologyPancreatic Islet SecretionSerotonergic MechanismsSerotonergic Modulation
receptors reduces glucagon secretion and has hypoglycemic effects in diabetic mice. Thus, modulation of serotonin signaling in the islet represents a drug intervention opportunity.
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Hail Kim, Yukiko Toyofuku, Francis C. Lynn et al. · Nature Medicine · 2010 · 583 citations · Full text
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