Camilla Silvander

Structural Basis for Phosphoinositide Substrate Recognition, Catalysis, and Membrane Interactions in Human Inositol Polyphosphate 5-Phosphatases

L. Tresaugues, Camilla Silvander, S. Flodin et al. · Structure · 2014 · 61 citations

Proteinlipid Interaction, Signal Transduction, Cellular Enzymology +11

Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target

Manuel Ellermann, Ashley Eheim, Fredrik Rahm et al. · ACS Chemical Biology · 2017 · 57 citations · Full text

Broad-spectrum Cancer Target, Cancer Dependency, Present Bay-707 +12

Creation of a Novel Class of Potent and Selective MutT Homologue 1 (MTH1) Inhibitors Using Fragment-Based Screening and Structure-Based Drug Design

Fredrik Rahm, Jenny Viklund, L. Tresaugues et al. · Journal of Medicinal Chemistry · 2018 · 33 citations · Full text

Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate

L. Tresaugues, Thomas Lundbäck, M. Welin et al. · PLoS ONE · 2015 · 25 citations · Full text

Crystal Structures of Type-II Inositol Polyphosphate 5-Phosphatase INPP5B with Synthetic Inositol Polyphosphate Surrogates Reveal New Mechanistic Insights for the Inositol 5-Phosphatase Family

Stephen Mills, Camilla Silvander, Gyles E. Cozier et al. · Biochemistry · 2016 · 17 citations · Full text

Proteinlipid Interaction, Signal Transduction, Synthetic Benzene +14