Mengzhao Xun

AAV1-hOTOF gene therapy for autosomal recessive deafness 9: a single-arm trial

Jun Lv, Hui Wang, Xiaoting Cheng et al. · The Lancet · 2024 · 325 citations

Medicine, Genetics, Molecular Genetics +10

Bilateral gene therapy in children with autosomal recessive deafness 9: single-arm trial results

Hui Wang, Yuxin Chen, Jun Lv et al. · Nature Medicine · 2024 · 124 citations · Full text

Medicine, Audiology, Genetics +15

Hearing of Otof-deficient mice restored by trans-splicing of N- and C-terminal otoferlin

Honghai Tang, Hui Wang, Shengyi Wang et al. · Human Genetics · 2022 · 82 citations

Medicine, Molecular Biology, Molecular Genetics +11

Preclinical evaluation of the efficacy and safety of AAV1-hOTOF in mice and nonhuman primates

Longlong Zhang, Hui Wang, Mengzhao Xun et al. · Molecular Therapy — Methods & Clinical Development · 2023 · 45 citations · Full text

Life Sciences, Molecular Medicine, Molecular Virology +7

Hair cell-specific Myo15 promoter-mediated gene therapy rescues hearing in DFNB9 mouse model

Hui Wang, Mengzhao Xun, Honghai Tang et al. · Molecular Therapy — Nucleic Acids · 2024 · 30 citations · Full text

Medicine, Genetics, Molecular Genetics +17