Yuxin Chen

AAV1-hOTOF gene therapy for autosomal recessive deafness 9: a single-arm trial

Jun Lv, Hui Wang, Xiaoting Cheng et al. · The Lancet · 2024 · 277 citations

Gene Therapies, Aav1-hotof Gene Therapy, Single-arm Trial +6

Bilateral gene therapy in children with autosomal recessive deafness 9: single-arm trial results

Hui Wang, Yuxin Chen, Jun Lv et al. · Nature Medicine · 2024 · 99 citations · Full text

Structural insights into the lipid and ligand regulation of a human neuronal KCNQ channel

You Zheng, Heng Liu, Yuxin Chen et al. · Neuron · 2021 · 76 citations

Molecular Physiology, Molecular Neuroscience, Biochemistry +13

Hearing of Otof-deficient mice restored by trans-splicing of N- and C-terminal otoferlin

Honghai Tang, Hui Wang, Shengyi Wang et al. · Human Genetics · 2022 · 74 citations

C-terminal Otoferlin, Developmental Biology, Otof-deficient Mice +10

Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors

Yikai Luo, Yu Xia, Dan Liu et al. · Cell · 2024 · 69 citations · Full text