Concepedia

Irena Loryan

IL

Statistics

Publications

21

Citations

957

H-Index

17

Active since

2011

Affiliations

Uppsala University(Current)

Science for Life Laboratory

Janssen (Belgium)

Karolinska Institutet

Erasmus MC

Irena Loryan is an author at Uppsala University specializing in pharmacology, blood-brain barrier penetration, and pharmacokinetics.

ORCID

Publications per year

2011–2024

21

Publications

21

Unbound Brain-to-Plasma Partition Coefficient, Kp,uu,brain—a Game Changing Parameter for CNS Drug Discovery and Development

Irena Loryan, Andreas Reichel, Bo Feng et al. · Pharmaceutical Research · 2022 · 151 citations · Full text

, , +14

The brain slice method for studying drug distribution in the CNS

Irena Loryan, Markus Fridén, Margareta Hammarlund‐Udenaes · Fluids and Barriers of the CNS · 2013 · 100 citations · Full text

, , +17

Mechanistic Understanding of Brain Drug Disposition to Optimize the Selection of Potential Neurotherapeutics in Drug Discovery

Irena Loryan, Vikash Sinha, Claire Mackie et al. · Pharmaceutical Research · 2014 · 90 citations

, , +17

Influence of sex on propofol metabolism, a pilot study: implications for propofol anesthesia

Irena Loryan, M. Lindqvist, Inger Johansson et al. · European Journal of Clinical Pharmacology · 2011 · 81 citations

, , +12

In-depth neuropharmacokinetic analysis of antipsychotics based on a novel approach to estimate unbound target-site concentration in CNS regions: link to spatial receptor occupancy

Irena Loryan, Erik Melander, Marcus Svensson et al. · Molecular Psychiatry · 2016 · 69 citations

, , +16

1–5 of 21