Vikash Sinha

Mechanistic Understanding of Brain Drug Disposition to Optimize the Selection of Potential Neurotherapeutics in Drug Discovery

Irena Loryan, Vikash Sinha, Claire Mackie et al. · Pharmaceutical Research · 2014 · 89 citations

Drug Repositioning, Drug Target, Neurophysiology +11

Urinary Tubular Protein-Based Biomarkers in the Rodent Model of Cisplatin Nephrotoxicity: A Comparative Analysis of Serum Creatinine, Renal Histology, and Urinary KIM-1, NGAL, and NAG in the Initiation, Maintenance, and Recovery Phases of Acute Kidney Injury

Vikash Sinha, Luis M. Vence, Abdulla K. Salahudeen · Journal of Investigative Medicine · 2013 · 64 citations

Molecular Properties Determining Unbound Intracellular and Extracellular Brain Exposure of CNS Drug Candidates

Irena Loryan, Vikash Sinha, Claire Mackie et al. · Molecular Pharmaceutics · 2014 · 63 citations

Drug Target, Neurochemical Biomarkers, Unbound Drug +22

Profiling the dynamics of CSF and plasma Aβ reduction after treatment with JNJ‐54861911, a potent oral BACE inhibitor

Maarten Timmers, Bianca Van Broeck, Steven Ramael et al. · Alzheimer s & Dementia Translational Research & Clinical Interventions · 2016 · 59 citations · Full text

Pharmacokinetic and pharmacodynamic characterisation of JNJ-40411813, a positive allosteric modulator of mGluR2, in two randomised, double-blind phase-I studies

Hiba Salih, Ion Anghelescu, Iva Kezic et al. · Journal of Psychopharmacology · 2015 · 49 citations