Claire Mackie

MetaSite:  Understanding Metabolism in Human Cytochromes from the Perspective of the Chemist

Gabriele Cruciani, Emanuele Carosati, Benoît De Boeck et al. · Journal of Medicinal Chemistry · 2005 · 491 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Prediction of Human Pharmacokinetics Using Physiologically Based Modeling: A Retrospective Analysis of 26 Clinically Tested Drugs

Stefan S. De Buck, Vikash K. Sinha, Luca A. Fenu et al. · Drug Metabolism and Disposition · 2007 · 253 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Biased mGlu 5 -Positive Allosteric Modulators Provide In Vivo Efficacy without Potentiating mGlu 5 Modulation of NMDAR Currents

Jerri M. Rook, Zixiu Xiang, Xiaohui Lv et al. · Neuron · 2015 · 129 citations · Full text

Life Sciences, Neuroscience, Pharmacology +16

Anxiolytic- and antidepressant-like profile of a new CRF1 receptor antagonist, R278995/CRA0450

Shigeyuki Chaki, Atsuro Nakazato, Ludo Kennis et al. · European Journal of Pharmacology · 2003 · 123 citations

Medicine, Pharmacology, Psychiatry +14

Evaluation of various PAMPA models to identify the most discriminating method for the prediction of BBB permeability

J. Mensch, A. Melis, Claire Mackie et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2010 · 123 citations

Engineering, Materials Science, Transport Phenomena +7