Stefan S. De Buck

Phase I, Dose-Escalation Study of BKM120, an Oral Pan-Class I PI3K Inhibitor, in Patients With Advanced Solid Tumors

Johanna C. Bendell, Jordi Rodón, Howard A. Burris et al. · Journal of Clinical Oncology · 2011 · 679 citations · Full text

Prediction of Human Pharmacokinetics Using Physiologically Based Modeling: A Retrospective Analysis of 26 Clinically Tested Drugs

Stefan S. De Buck, Vikash K. Sinha, Luca A. Fenu et al. · Drug Metabolism and Disposition · 2007 · 251 citations

The Prediction of Drug Metabolism, Tissue Distribution, and Bioavailability of 50 Structurally Diverse Compounds in Rat Using Mechanism-Based Absorption, Distribution, and Metabolism Prediction Tools

Stefan S. De Buck, Vikash K. Sinha, Luca A. Fenu et al. · Drug Metabolism and Disposition · 2007 · 92 citations

A first-in-human phase I study of BKM120, an oral pan-class I PI3K inhibitor, in patients (pts) with advanced solid tumors.

José Baselga, Maja J. De Jonge, Jordi Rodón et al. · Journal of Clinical Oncology · 2010 · 53 citations

Pathology, Pi3k Inhibitor, Pharmacotherapy +16

Predicting Oral Clearance in Humans

Vikash K. Sinha, Stefan S. De Buck, Luca A. Fenu et al. · Clinical Pharmacokinetics · 2008 · 49 citations

Oral Cavity, Oral Hygiene, Oral Clearance +2