Barbara L. Gaffney

Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

Pu Gao, Manuel Ascano, Yang Wu et al. · Cell · 2013 · 1.1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA

Pu Gao, Manuel Ascano, Thomas Zillinger et al. · Cell · 2013 · 581 citations · Full text

Medicine, Molecular Biology, Pharmacology +13

Transient protection: efficient one-flask syntheses of protected deoxynucleosides

Gavrilova Ti, Barbara L. Gaffney, Roger A. Jones · Journal of the American Chemical Society · 1982 · 389 citations

Pharmacy, Chemistry, Analytical Chemistry +4

Thermodynamics and structure of a DNA tetraplex: a spectroscopic and calorimetric study of the tetramolecular complexes of d(TG3T) and d(TG3T2G3T).

Rongchao Jin, Barbara L. Gaffney, Chao Wang et al. · Proceedings of the National Academy of Sciences · 1992 · 185 citations

Natural Sciences, Biochemistry, Biophysics +17

Structures of HIV-1 RT–DNA complexes before and after incorporation of the anti-AIDS drug tenofovir

Steve Tuske, Stefan G. Sarafianos, Arthur D. Clark et al. · Nature Structural & Molecular Biology · 2004 · 162 citations

Life Sciences, Biology, Molecular Biology +13