Taku Okazaki

Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

Gordon J. Freeman, Andrew J. Long, Yoshiko Iwai et al. · The Journal of Experimental Medicine · 2000 · 5.2K citations · Full text

Life Sciences, Immunology, Pathology +17

Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade

Yoshiko Iwai, Masayoshi Ishida, Yoshimasa Tanaka et al. · Proceedings of the National Academy of Sciences · 2002 · 3.2K citations

Life Sciences, Immunology, Oncology +17

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

Yvette Latchman, Clive R. Wood, Tatyana Chernova et al. · Nature Immunology · 2001 · 2.9K citations

Life Sciences, Cell Biology, Immunology +14

Autoimmune Dilated Cardiomyopathy in PD-1 Receptor-Deficient Mice

Hiroyuki Nishimura, Taku Okazaki, Yoshimasa Tanaka et al. · Science · 2001 · 1.9K citations

Life Sciences, Cardiology, Pathology +11

Programmed cell death 1 ligand 1 and tumor-infiltrating CD8 ⁺ T lymphocytes are prognostic factors of human ovarian cancer

Junzo Hamanishi, Masaki Mandai, Masashi Iwasaki et al. · Proceedings of the National Academy of Sciences · 2007 · 1.4K citations · Full text

Medicine, Immunology, Oncology +17