Ashley Hale

Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation

Jade Bailey, Marina Diotallevi, T. NICOL et al. · Cell Reports · 2019 · 265 citations · Full text

Life Sciences, Biochemistry, Immunology +17

Rapid, Direct Effects of Statin Treatment on Arterial Redox State and Nitric Oxide Bioavailability in Human Atherosclerosis via Tetrahydrobiopterin-Mediated Endothelial Nitric Oxide Synthase Coupling

Charalambos Antoniades, Constantinos Bakogiannis, Paul Leeson et al. · Circulation · 2011 · 218 citations · Full text

Medicine, Cardiology, Pharmacology +17

Critical Role for Tetrahydrobiopterin Recycling by Dihydrofolate Reductase in Regulation of Endothelial Nitric-oxide Synthase Coupling

Mark J. Crabtree, Amy L. Tatham, Ashley Hale et al. · Journal of Biological Chemistry · 2009 · 208 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Extended plasma circulation time and decreased toxicity of polymer-coated adenovirus

N K Green, Sarah Hale, Ashley Hale et al. · Gene Therapy · 2004 · 203 citations

Pharmacy, Molecular Pharmaceutics, Pharmacokinetics +12

Quantitative Regulation of Intracellular Endothelial Nitric-oxide Synthase (eNOS) Coupling by Both Tetrahydrobiopterin-eNOS Stoichiometry and Biopterin Redox Status

Mark J. Crabtree, Amy L. Tatham, Yasir Al-Wakeel et al. · Journal of Biological Chemistry · 2008 · 192 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13