Amy L. Tatham

Critical Role for Tetrahydrobiopterin Recycling by Dihydrofolate Reductase in Regulation of Endothelial Nitric-oxide Synthase Coupling

Mark J. Crabtree, Amy L. Tatham, Ashley Hale et al. · Journal of Biological Chemistry · 2009 · 208 citations · Full text

Aldo-keto Reductase, Dhfr Inhibition, Molecular Biology +19

Quantitative Regulation of Intracellular Endothelial Nitric-oxide Synthase (eNOS) Coupling by Both Tetrahydrobiopterin-eNOS Stoichiometry and Biopterin Redox Status

Mark J. Crabtree, Amy L. Tatham, Yasir Al-Wakeel et al. · Journal of Biological Chemistry · 2008 · 191 citations · Full text

Biopterin Redox Status, Tetrahydrobiopterin-enos Stoichiometry, Redox Biology +20

Endothelial Nox2 Overexpression Potentiates Vascular Oxidative Stress and Hemodynamic Response to Angiotensin II

Jennifer K. Bendall, Ruth Rinze, David Adlam et al. · Circulation Research · 2007 · 153 citations

Hypertension, Nadph Oxidase, Lipid Peroxidation +18

Endothelial-specific Nox2 overexpression increases vascular superoxide and macrophage recruitment in ApoE−/− mice

Gillian Douglas, Jennifer K. Bendall, Mark J. Crabtree et al. · Cardiovascular Research · 2012 · 108 citations · Full text

GTP Cyclohydrolase I Expression, Protein, and Activity Determine Intracellular Tetrahydrobiopterin Levels, Independent of GTP Cyclohydrolase Feedback Regulatory Protein Expression

Amy L. Tatham, Mark J. Crabtree, N Warrick et al. · Journal of Biological Chemistry · 2009 · 59 citations · Full text

Lipid Peroxidation, Immunology, Molecular Biology +20