Antitumor efficacy of piperine in the treatment of human HER2-overexpressing breast cancer cells

Minh Truong, Hyung Gyun Kim, Jae Ho Choi, +5

Food Chemistry

Breast OncologyMedicinePharmacologyAntitumor EfficacyBreast Cancer +4

Anthocyanins from purple sweet potato attenuate dimethylnitrosamine-induced liver injury in rats by inducing Nrf2-mediated antioxidant enzymes and reducing COX-2 and iNOS expression

Yong Pil Hwang, Jae Ho Choi, Hyo Jeong Yun, +8

Food and Chemical Toxicology

BiochemistryNrf2-mediated Antioxidant EnzymesMedicineLiver PhysiologyToxicology +7

Metformin inhibits heme oxygenase-1 expression in cancer cells through inactivation of Raf-ERK-Nrf2 signaling and AMPK-independent pathways

Minh Truong, Hyung Gyun Kim, Tilak Khanal, +4

Toxicology and Applied Pharmacology

MedicineHeme Oxygenase-1 ExpressionCancer Cell BiologyAmpk-independent PathwaysCancer Biology +7

Piperine inhibits PMA-induced cyclooxygenase-2 expression through downregulating NF-κB, C/EBP and AP-1 signaling pathways in murine macrophages

Hyung Gyun Kim, Eun Hee Han, Woo-seok Jang, +6

Food and Chemical Toxicology

InflammationCytokineAnti-inflammatoryMedicineImmunology +8

Phillyrin attenuates high glucose-induced lipid accumulation in human HepG2 hepatocytes through the activation of LKB1/AMP-activated protein kinase-dependent signalling

Minh Truong, Hyung Gyun Kim, Jae Ho Choi, +6

Food Chemistry

Metabolic SyndromeSignal TransductionBiochemistryMedicineLiver Physiology +9

Saponins isolated from the root of Platycodon grandiflorum protect against acute ethanol-induced hepatotoxicity in mice

Tilak Khanal, Jae Ho Choi, Yong Pil Hwang, +2

Food and Chemical Toxicology

Platycodon Grandiflorum ProtectMedicineLiver PhysiologyPhytopharmacologyToxicology +6

Platycodon grandiflorum root-derived saponins attenuate atopic dermatitis-like skin lesions via suppression of NF-κB and STAT1 and activation of Nrf2/ARE-mediated heme oxygenase-1

Jae Ho Choi, Sun Woo Jin, Eun Hee Han, +10

Phytomedicine

InflammationAllergyAtopic DermatitisRoot-derived SaponinsDermatitis-like Skin Lesions +10

Protective effect of caffeic acid phenethyl ester against carbon tetrachloride-induced hepatotoxicity in mice

Kyung Jin Lee, Jae Ho Choi, Tilak Khanal, +3

Toxicology

BiochemistryMedicineLiver PhysiologyToxicologyHepatotoxicity +8

Role of metabolism by human intestinal microflora in geniposide-induced toxicity in HepG2 cells

Mi Jeong Kang, Tilak Khanal, Hyung Gyun Kim, +7

Archives of Pharmacal Research

Human Intestinal MicrofloraGeniposide-induced ToxicityBiochemistryMedicineLiver Physiology +11

Cultivated ginseng inhibits 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in NC/Nga mice and TNF-α/IFN-γ-induced TARC activation in HaCaT cells

Jae Ho Choi, Sun Woo Jin, Bong Hwan Park, +9

Food and Chemical Toxicology

InflammationHacat CellsAtopic DermatitisImmunologyImmune Regulation +9