Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent

Dean R. Artis, Jack J. Lin, Chao Zhang, +31

Proceedings of the National Academy of Sciences

Metabolic SyndromeMedicinal ChemistryBiochemistryG Protein-coupled ReceptorMedicine +13

The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1

Weiru Wang, Chao Zhang, Adhirai Marimuthu, +10

Proceedings of the National Academy of Sciences

Molecular BiologyTranscriptional RegulationRegulatory LigandsSignaling PathwaySex Determination +18

Inhibition of Soluble Epoxide Hydrolase Attenuated Atherosclerosis, Abdominal Aortic Aneurysm Formation, and Dyslipidemia

Le-Ning Zhang, Jon Vincelette, Ying Cheng, +6

Arteriosclerosis Thrombosis and Vascular Biology

1-(1-Acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia

Sampath‐Kumar Anandan, Heather K. Webb, Dawn Chen, +19

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryOxysterolBiochemistryMedicineNatural Sciences +5

High-Throughput Screening of Formulations to Optimize the Thermal Stability of a Therapeutic Monoclonal Antibody

Anita Niedziela‐Majka, Elaine Kan, Perry Weissburg, +3

SLAS DISCOVERY

EngineeringBiomedical EngineeringImmunotherapyProtein FoldingBioanalysis +14

Hepatitis B Virus X Protein Function Requires Zinc Binding

Dhivya Ramakrishnan, Weimei Xing, Rudolf K. Beran, +12

Journal of Virology

Novel Scintillation Proximity Assay for Measuring Membrane-Associated Steps of Peptidoglycan Biosynthesis in <i>Escherichia coli</i>

B. Chandrakala, Bertha C. Elias, Upasana Mehra, +4

Antimicrobial Agents and Chemotherapy

High-Throughput Screen for Inhibitors of Transglycosylase and/or Transpeptidase Activities of <i>Escherichia coli</i> Penicillin Binding Protein 1b

B. Chandrakala, Radha Krishan Shandil, Upasana Mehra, +5

Antimicrobial Agents and Chemotherapy

Characterization of a Novel Capsid Assembly Modulator for the Treatment of Chronic Hepatitis B Virus Infection

Dara Burdette, Anastasia Hyrina, Zhijuan Song, +21

Antimicrobial Agents and Chemotherapy

<i>MRX8</i>, the conserved mitochondrial YihA GTPase family member, is required for de novo Cox1 synthesis at suboptimal temperatures in <i>Saccharomyces cerevisiae</i>

Yash Verma, Upasana Mehra, Dharmendra Kumar Pandey, +4

Molecular Biology of the Cell