Thomas De Raedt

PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies

Thomas De Raedt, Eline Beert, Éric Pasmant et al. · Nature · 2014 · 461 citations

Transcriptional Regulation, Cell Regulation, Cell Signaling +12

An oncogene–tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-κB

Junxia Min, A. Zaslavsky, Giuseppe Fedele et al. · Nature Medicine · 2010 · 377 citations · Full text

Nuclear Factor-κb, Oncogenic Agent, Medicine +6

Elevated Risk for MPNST in NF1 Microdeletion Patients

Thomas De Raedt, Hilde Brems, P. Wolkenstein et al. · The American Journal of Human Genetics · 2003 · 301 citations · Full text

Genetic Epidemiology, Risk, Pathology +2

Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance

Nobuaki Takahashi, Hsing‐Yu Chen, Isaac S. Harris et al. · Cancer Cell · 2018 · 271 citations · Full text

Redox Signaling, Cancer Research, Oxidative-stress Tolerance +12

Exploiting Cancer Cell Vulnerabilities to Develop a Combination Therapy for Ras-Driven Tumors

Thomas De Raedt, Zandra E. Walton, Jessica L. Yecies et al. · Cancer Cell · 2011 · 257 citations · Full text

Tumor Biology, Cancer Cell Vulnerabilities, Medicine +12