Jaime M. Reyes

BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment

Georg Winter, Andreas Mayer, Dennis L. Buckley et al. · Molecular Cell · 2017 · 467 citations · Full text

Transcriptional Regulation, Cell Regulation, Genetics +7

Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms

Maria Kleppe, Richard P. Koche, Lihua Zou et al. · Cancer Cell · 2017 · 277 citations · Full text

Hematological Malignancy, Oncogenic Activation, Malignant Blood Disorder +10

Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo

Mira Jeong, Hyun Jung Park, Hamza Celik et al. · Cell Reports · 2018 · 258 citations · Full text

Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma

Rhamy Zeid, Matthew A. Lawlor, Evon Poon et al. · Nature Genetics · 2018 · 237 citations · Full text

Cell Regulation, Mycn-dependent Transcriptional Amplification, Medicine +2

Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands

Lara Gechijian, Dennis L. Buckley, Matthew A. Lawlor et al. · Nature Chemical Biology · 2018 · 221 citations · Full text

Vhl Ligands, Medicinal Chemistry, Biochemistry +4