Matthew A. Lawlor

The dTAG system for immediate and target-specific protein degradation

Behnam Nabet, Justin M. Roberts, Dennis L. Buckley et al. · Nature Chemical Biology · 2018 · 1.1K citations · Full text

Protein Function, Protein Expression, Protein Folding +6

Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies

Romain Guièze, Vivian M. Liu, Daniel Rosebrock et al. · Cancer Cell · 2019 · 348 citations · Full text

Lymphoid Neoplasia, Mitochondrial Function, Medicine +9

Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma

Rhamy Zeid, Matthew A. Lawlor, Evon Poon et al. · Nature Genetics · 2018 · 237 citations · Full text

Cell Regulation, Mycn-dependent Transcriptional Amplification, Medicine +2

Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands

Lara Gechijian, Dennis L. Buckley, Matthew A. Lawlor et al. · Nature Chemical Biology · 2018 · 221 citations · Full text

Vhl Ligands, Medicinal Chemistry, Biochemistry +4

Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia

Christopher J. Ott, Alexander Federation, Logan S. Schwartz et al. · Cancer Cell · 2018 · 168 citations · Full text

Hematological Malignancy, Chromatin, Transcriptional Regulation +10