Richard P. Koche

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

Tarjei S. Mikkelsen, Manching Ku, David B. Jaffe et al. · Nature · 2007 · 4.1K citations · Full text

Chromatin, Chromatin Structure, Chromatin State +12

Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains

Manching Ku, Richard P. Koche, Esther Rheinbay et al. · PLoS Genetics · 2008 · 993 citations · Full text

ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression

Omar Abdel‐Wahab, Mazhar Adli, Lindsay M. LaFave et al. · Cancer Cell · 2012 · 585 citations · Full text

Hematological Malignancy, Chromatin, Somatic Variant +8

Loss of BAP1 function leads to EZH2-dependent transformation

Lindsay M. LaFave, Wendy Béguelin, Richard P. Koche et al. · Nature Medicine · 2015 · 392 citations · Full text

Chromatin, Signal Transduction, Signal Recognition +3

GC-Rich Sequence Elements Recruit PRC2 in Mammalian ES Cells

Eric M. Mendenhall, Richard P. Koche, Thanh Tung Truong et al. · PLoS Genetics · 2010 · 392 citations · Full text

Genetics, Genomic Mechanism, Epigenetics +16