Ana Isabel de Lucas

Discovery of 3-Cyclopropylmethyl-7-(4-phenylpiperidin-1-yl)-8-trifluoromethyl[1,2,4]triazolo[4,3-<i>a</i>]pyridine (JNJ-42153605): A Positive Allosteric Modulator of the Metabotropic Glutamate 2 Receptor

José M. Cid, Gary Tresadern, Juan A. Vega et al. · Journal of Medicinal Chemistry · 2012 · 84 citations · Full text

Rem Sleep State, Pharmacotherapy, Mglu2 Receptor Pams +22

Scaffold hopping from pyridones to imidazo[1,2-a]pyridines. New positive allosteric modulators of metabotropic glutamate 2 receptor

Gary Tresadern, José M. Cid, Gregor J. Macdonald et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 73 citations · Full text

Scaffold Hopping, Metabotropic Glutamate 2, Biochemistry +7

The first tetrathiafulvalene derivatives exhibiting second-order NLO properties

Ana Isabel de Lucas, Nazario Martı́n, Luis Sánchez et al. · Tetrahedron · 1998 · 70 citations

Derivative (Chemistry), Natural Sciences, Applied Physics +4

Imidazo[1,2-<i>a</i>]pyridines: Orally Active Positive Allosteric Modulators of the Metabotropic Glutamate 2 Receptor

Andrés A. Trabanco, Gary Tresadern, Gregor J. Macdonald et al. · Journal of Medicinal Chemistry · 2012 · 60 citations · Full text

Pharmacotherapy, Molecular Pharmacology, Medicinal Chemistry +17

Discovery of 1-Butyl-3-chloro-4-(4-phenyl-1-piperidinyl)-(1 <i>H</i> )-pyridone (JNJ-40411813): A Novel Positive Allosteric Modulator of the Metabotropic Glutamate 2 Receptor

José M. Cid, Gary Tresadern, Guillaume Duvey et al. · Journal of Medicinal Chemistry · 2014 · 56 citations · Full text