Charles Jayne

Statistics

Publications

Citations

159

H-Index

Active since

2011

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

United States Military Academy

Charles Jayne is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in drug discovery, medicinal chemistry, and pharmacology.

ORCID

Publications per year

2011–2023

Publications

Discovery of a nortropanol derivative as a potent and orally active GPR119 agonist for type 2 diabetes

Yan Xia, Samuel Chackalamannil, William J. Greenlee et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 43 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +6

Discovery of MK-8831, A Novel Spiro-Proline Macrocycle as a Pan-Genotypic HCV-NS3/4a Protease Inhibitor

Santhosh Neelamkavil, Sony Agrawal, Thomas Bara et al. · ACS Medicinal Chemistry Letters · 2015 · 34 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Discovery of Chromane Propionic Acid Analogues as Selective Agonists of GPR120 with <i>in Vivo</i> Activity in Rodents

Gregory L. Adams, Francisco Velázquez, Charles Jayne et al. · ACS Medicinal Chemistry Letters · 2016 · 32 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Novel Quinoline-Based P2–P4 Macrocyclic Derivatives As Pan-Genotypic HCV NS3/4a Protease Inhibitors

Unmesh Shah, Charles Jayne, Samuel Chackalamannil et al. · ACS Medicinal Chemistry Letters · 2014 · 25 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synthesis of DNA-Encoded Macrocyclic Peptides via Nitrile-Aminothiol Click Reaction

Lijun Fan, Yang Yu, Charles Jayne et al. · Organic Letters · 2023 · 15 citations

Pharmacy, Medicinal Chemistry, Molecular Biology +17

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