Sony Agrawal

Discovery of (1 <i>R</i> ,5 <i>S</i> )- <i>N</i> -[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2( <i>S</i> )-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2( <i>S</i> )-carboxamide (SCH 503034), a Selective, Potent, Orally Bioavailable Hepatitis C Virus NS3 Protease Inhibitor:  A Potential Therapeutic Agent for the Treatment of Hepatitis C Infection

Srikanth Venkatraman, Stéphane Bogen, Ashok Arasappan et al. · Journal of Medicinal Chemistry · 2006 · 278 citations · Full text

Discovery of SCH446211 (SCH6):  A New Ketoamide Inhibitor of the HCV NS3 Serine Protease and HCV Subgenomic RNA Replication

Stéphane Bogen, Ashok Arasappan, Frank Bennett et al. · Journal of Medicinal Chemistry · 2006 · 59 citations · Full text

Viral Replication, Immunology, Molecular Biology +16

Discovery and Structure−Activity Relationship of P₁−P₃ Ketoamide Derived Macrocyclic Inhibitors of Hepatitis C Virus NS3 Protease

Srikanth Venkatraman, Francisco Velázquez, Wanli Wu et al. · Journal of Medicinal Chemistry · 2008 · 52 citations · Full text

Analogue 52, Antiviral Compound, Hepatology +15

I. Novel HCV NS5B polymerase inhibitors: Discovery of indole 2-carboxylic acids with C3-heterocycles

G. Anilkumar, Charles A. Lesburg, Oleg Selyutin et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 49 citations

Biochemistry, Medicine, Indole 2-Carboxylic Acids +5

Discovery of Ruzasvir (MK-8408): A Potent, Pan-Genotype HCV NS5A Inhibitor with Optimized Activity against Common Resistance-Associated Polymorphisms

Ling Tong, Wensheng Yu, Lei Chen et al. · Journal of Medicinal Chemistry · 2016 · 47 citations

Medicinal Chemistry, Antiviral Compound, Molecular Virology +14