Concepedia

Lei Chen

LC

18

Publications

347

Citations

14

H-Index

2010

Active since

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

WuXi AppTec (China)

United States Military Academy

Southern Research Institute

Lei Chen is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in medicine, drug discovery, and pharmacology.

ORCID

Top concepts

Publications per year

2010–2018

18

Publications

18

Discovery of Ruzasvir (MK-8408): A Potent, Pan-Genotype HCV NS5A Inhibitor with Optimized Activity against Common Resistance-Associated Polymorphisms

Ling Tong, Wensheng Yu, Lei Chen et al. · Journal of Medicinal Chemistry · 2016 · 47 citations

, , +14

Discovery of Chromane Containing Hepatitis C Virus (HCV) NS5A Inhibitors with Improved Potency against Resistance-Associated Variants

Wensheng Yu, Ling Tong, Bin Hu et al. · Journal of Medicinal Chemistry · 2016 · 28 citations

, , +19

Discovery of silyl proline containing HCV NS5A inhibitors with pan-genotype activity: SAR development

Anilkumar G. Nair, Qingbei Zeng, Oleg Selyutin et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 27 citations · Full text

, , +8

Biaryl substituted hydantoin compounds as TACE inhibitors

Wensheng Yu, Ling Tong, Seong Heon Kim et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 26 citations · Full text

, , +6

Novel TNF-α converting enzyme (TACE) inhibitors as potential treatment for inflammatory diseases

Vinay Girijavallabhan, Lei Chen, Chaoyang Dai et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 22 citations · Full text

, , +13

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