Concepedia

Lei Chen

LC

Statistics

Publications

19

Citations

359

H-Index

14

Active since

2010

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

WuXi AppTec (China)

United States Military Academy

Southern Research Institute

Lei Chen is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in medicinal chemistry, pharmacology, and drug discovery.

ORCID

Publications per year

2010–2024

19

Publications

19

Discovery of Ruzasvir (MK-8408): A Potent, Pan-Genotype HCV NS5A Inhibitor with Optimized Activity against Common Resistance-Associated Polymorphisms

Ling Tong, Wensheng Yu, Lei Chen et al. · Journal of Medicinal Chemistry · 2016 · 47 citations · Full text

, , +17

Discovery of Chromane Containing Hepatitis C Virus (HCV) NS5A Inhibitors with Improved Potency against Resistance-Associated Variants

Wensheng Yu, Ling Tong, Bin Hu et al. · Journal of Medicinal Chemistry · 2016 · 28 citations

, , +17

Biaryl substituted hydantoin compounds as TACE inhibitors

Wensheng Yu, Ling Tong, Seong Heon Kim et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 27 citations · Full text

, , +13

Discovery of silyl proline containing HCV NS5A inhibitors with pan-genotype activity: SAR development

Anilkumar G. Nair, Qingbei Zeng, Oleg Selyutin et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 27 citations · Full text

, , +15

Novel TNF-α converting enzyme (TACE) inhibitors as potential treatment for inflammatory diseases

Vinay Girijavallabhan, Lei Chen, Chaoyang Dai et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 23 citations · Full text

, , +16

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