Concepedia

Thomas Bara

TB

17

Publications

1.3K

Citations

15

H-Index

2002

Active since

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

AIL Research (United States)

LabCorp (United States)

Thomas Bara is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in medicine, natural sciences, and drug discovery.

Top concepts

Publications per year

2002–2016

17

Publications

17

Chronic Treatment with the γ-Secretase Inhibitor LY-411,575 Inhibits β-Amyloid Peptide Production and Alters Lymphopoiesis and Intestinal Cell Differentiation

Gwendolyn T. Wong, Denise Manfra, Frederique M. Poulet et al. · Journal of Biological Chemistry · 2004 · 715 citations · Full text

Synthesis, SAR, and Biological Evaluation of Oximino-Piperidino-Piperidine Amides. 1. Orally Bioavailable CCR5 Receptor Antagonists with Potent Anti-HIV Activity

Anandan Palani, Sherry Shapiro, Hubert Josien et al. · Journal of Medicinal Chemistry · 2002 · 79 citations · Full text

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Studies to Investigate the in Vivo Therapeutic Window of the γ-Secretase Inhibitor N2-[(2 S)-2-(3,5-Difluorophenyl)-2-hydroxyethanoyl]-N1-[(7 S)-5-methyl-6-oxo-6,7-dihydro-5 H-dibenzo[b,d]azepin-7-yl]-l-alaninamide (LY411,575) in the CRND8 Mouse

Lynn A. Hyde, Nansie A. McHugh, Joseph Chen et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 68 citations

Cyclic Hydroxyamidines as Amide Isosteres: Discovery of Oxadiazolines and Oxadiazines as Potent and Highly Efficacious γ-Secretase Modulators in Vivo

Z. J. Sun, Theodros Asberom, Thomas Bara et al. · Journal of Medicinal Chemistry · 2011 · 52 citations · Full text

2,6-Disubstituted N-arylsulfonyl piperidines as γ-secretase inhibitors

Dmitri Pissarnitski, Theodros Asberom, Thomas Bara et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 39 citations · Full text

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