Ian C. Chute

DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells

Marie‐France Robert, Steves Morin, Normand Beaulieu et al. · Nature Genetics · 2002 · 611 citations

Life Sciences, Genetics, Molecular Biology +16

Characterization of a self-splicing mini-intein and its conversion into autocatalytic N- and C-terminal cleavage elements: facile production of protein building blocks for protein ligation

Sibylle Mathys, Thomas C. Evans, Ian C. Chute et al. · Gene · 1999 · 208 citations

Life Sciences, Biochemistry, Molecular Biology +12

Rapid Isolation of Extracellular Vesicles from Cell Culture and Biological Fluids Using a Synthetic Peptide with Specific Affinity for Heat Shock Proteins

Anirban Ghosh, Michelle Davey, Ian C. Chute et al. · PLoS ONE · 2014 · 187 citations · Full text

Life Sciences, Biochemistry, Cell Biology +11

An Essential Role for DNA Methyltransferase DNMT3B in Cancer Cell Survival

Normand Beaulieu, Steves Morin, Ian C. Chute et al. · Journal of Biological Chemistry · 2002 · 162 citations · Full text

Medicine, Cancer Biology, Molecular Biology +17

Discovery of a novel and potent series of thieno[3,2-b]pyridine-based inhibitors of c-Met and VEGFR2 tyrosine kinases

Stephen Claridge, Franck Raeppel, Marie‐Claude Granger et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 63 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13