Stephen Claridge

Discovery of a novel and potent series of thieno[3,2-b]pyridine-based inhibitors of c-Met and VEGFR2 tyrosine kinases

Stephen Claridge, Franck Raeppel, Marie‐Claude Granger et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 62 citations · Full text

Medicinal Chemistry, Biochemistry, Vegfr2 Tyrosine Kinases +11

Constrained (l-)-S-adenosyl-l-homocysteine (SAH) analogues as DNA methyltransferase inhibitors

Ljubomir Isakovic, Oscar M. Saavedra, David B. Llewellyn et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 51 citations · Full text

Dna Methyltransferase Inhibitors, Medicinal Chemistry, Biochemistry +4

N-(4-(6,7-Disubstituted-quinolin-4-yloxy)-3-fluorophenyl)-2-oxo-3-phenylimidazolidine-1-carboxamides: A novel series of dual c-Met/VEGFR2 receptor tyrosine kinase inhibitors

Michael R. Mannion, Stéphane Raeppel, Stephen Claridge et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 50 citations · Full text

Medicinal Chemistry, Drug Target, Novel Series +12

SAR around (l)-S-adenosyl-l-homocysteine, an inhibitor of human DNA methyltransferase (DNMT) enzymes

Oscar M. Saavedra, Ljubomir Isakovic, David B. Llewellyn et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 49 citations · Full text

Biochemistry, Natural Sciences, Epigenetic Change +7

Probing the importance of spacial and conformational domains in captopril analogs for angiotensin converting enzyme activity

Stephen Hanessian, Ulrich Reinhold, Michel Saulnier et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 42 citations · Full text

Molecular Pharmacology, Biochemistry, Medicine +12