Darren Powell

Ceramide Disables 3-Phosphoinositide Binding to the Pleckstrin Homology Domain of Protein Kinase B (PKB)/Akt by a PKCζ-Dependent Mechanism

Darren Powell, Éric Hajduch, Gursant Kular et al. · Molecular and Cellular Biology · 2003 · 349 citations · Full text

Intracellular ceramide synthesis and protein kinase Cζ activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells

Darren Powell, Sophie Turban, Alexander Gray et al. · Biochemical Journal · 2004 · 258 citations · Full text

p53 mRNA controls p53 activity by managing Mdm2 functions

Marco M. Candeias, Laurence Malbert-Colas, Darren Powell et al. · Nature Cell Biology · 2008 · 234 citations

Cell Regulation, Tumor Suppressor, P53 Mrna +3

Ceramide down‐regulates System A amino acid transport and protein synthesis in rat skeletal muscle cells

Russell Hyde, Éric Hajduch, Darren Powell et al. · The FASEB Journal · 2004 · 124 citations

Muscle Function, Amino Acid Metabolism, Cellular Physiology +21

High-affinity FRβ-specific CAR T cells eradicate AML and normal myeloid lineage without HSC toxicity

Rachel C. Lynn, Yang Feng, Keith Schutsky et al. · Leukemia · 2016 · 114 citations

Hsc Toxicity, Hematology, Immunology +8