Éric Hajduch

Ceramide Disables 3-Phosphoinositide Binding to the Pleckstrin Homology Domain of Protein Kinase B (PKB)/Akt by a PKCζ-Dependent Mechanism

Darren Powell, Éric Hajduch, Gursant Kular et al. · Molecular and Cellular Biology · 2003 · 349 citations · Full text

Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells.

Éric Hajduch, Dario R. Alessi, Brian A. Hemmings et al. · Diabetes · 1998 · 333 citations

Phosphatidylinositol 3-Kinase, Metabolic Remodeling, Cellular Physiology +22

Anti-lipolytic Action of AMP-activated Protein Kinase in Rodent Adipocytes

Marie Daval, F Diot-Dupuy, R Bazin et al. · Journal of Biological Chemistry · 2005 · 323 citations · Full text

Metabolic Remodeling, Cellular Physiology, Metabolic Syndrome +16

Intracellular ceramide synthesis and protein kinase Cζ activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells

Darren Powell, Sophie Turban, Alexander Gray et al. · Biochemical Journal · 2004 · 258 citations · Full text

Ceramide impairs the insulin-dependent membrane recruitment of Protein Kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells

Éric Hajduch, Anudharan Balendran, Ian H. Batty et al. · Diabetologia · 2001 · 229 citations · Full text

Molecular Physiology, Signal Transduction, Biochemistry +15