Adhiraj Lanba

A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects

Saswata Talukdar, Yingjiang Zhou, Dongmei Li et al. · Cell Metabolism · 2016 · 488 citations · Full text

Life Sciences, Biochemistry, Endocrinology +15

Inhibition of Acetyl-CoA Carboxylase 1 (ACC1) and 2 (ACC2) Reduces Proliferation and De Novo Lipogenesis of EGFRvIII Human Glioblastoma Cells

Jessica Jones, William P. Esler, Rushi S. Patel et al. · PLoS ONE · 2017 · 112 citations · Full text

Medicine, Oncology, Pharmacology +17

Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5)

Kim Huard, Janice A. Brown, Jessica Jones et al. · Scientific Reports · 2015 · 70 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose homeostasis

Emilio P. Mottillo, Eric M. Desjardins, Andreas M. Fritzen et al. · Molecular Metabolism · 2017 · 59 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

Optimization of a Dicarboxylic Series for in Vivo Inhibition of Citrate Transport by the Solute Carrier 13 (SLC13) Family

Kim Huard, J Gosset, Justin I. Montgomery et al. · Journal of Medicinal Chemistry · 2016 · 40 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17