Jacob C. Kimmel

Murine single-cell RNA-seq reveals cell-identity- and tissue-specific trajectories of aging

Jacob C. Kimmel, Lolita Penland, Nimrod D. Rubinstein et al. · Genome Research · 2019 · 201 citations · Full text

Lifespan Extension, Systems Biology, Developmental Biology +15

Semisupervised adversarial neural networks for single-cell classification

Jacob C. Kimmel, David R. Kelley · Genome Research · 2021 · 108 citations · Full text

Few-shot Learning, Scnym Models, Machine Learning +18

Aging induces aberrant state transition kinetics in murine muscle stem cells

Jacob C. Kimmel, Ara B. Hwang, Annarita Scaramozza et al. · Development · 2020 · 90 citations · Full text

Inferring cell state by quantitative motility analysis reveals a dynamic state system and broken detailed balance

Jacob C. Kimmel, Amy Y. Chang, Andrew S. Brack et al. · PLoS Computational Biology · 2018 · 64 citations · Full text

Oocyte, Engineering, Cell State +19

Diverse partial reprogramming strategies restore youthful gene expression and transiently suppress cell identity

Antoine E. Roux, Chunlian Zhang, Jonathan S. Paw et al. · Cell Systems · 2022 · 64 citations

Functional Genomics, Developmental Biology, Suppress Cell Identity +9