Geoffrey Neale

HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

Lewis Z. Shi, Ruoning Wang, Gonghua Huang et al. · The Journal of Experimental Medicine · 2011 · 1.8K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes

Rajendra Karki, Bhesh Raj Sharma, Shraddha Tuladhar et al. · Cell · 2020 · 1.7K citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +16

ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways

Teneema Kuriakose, Si Ming Man, R. K. Subbarao Malireddi et al. · Science Immunology · 2016 · 789 citations

Life Sciences, Immunology, Molecular Biology +17

De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation

Hazem E. Ghoneim, Yiping Fan, Ardiana Moustaki et al. · Cell · 2017 · 786 citations · Full text

Life Sciences, Immunology, Molecular Biology +10

mTORC1 couples immune signals and metabolic programming to establish Treg-cell function

Hu Zeng, Kai Yang, Caryn Cloer et al. · Nature · 2013 · 785 citations

Life Sciences, Immunology, Molecular Biology +16