Douglas K. Brubaker

Tissue-Specific Oncogenic Activity of KRASA146T

Emily J. Poulin, Asim K. Bera, Jia Lu et al. · Cancer Discovery · 2019 · 189 citations · Full text

Translating preclinical models to humans

Douglas K. Brubaker, Douglas A. Lauffenburger · Science · 2020 · 112 citations

Drug Repositioning, Engineering, Drug Target +15

Proteogenomic Network Analysis of Context-Specific KRAS Signaling in Mouse-to-Human Cross-Species Translation

Douglas K. Brubaker, João A. Paulo, Shikha Sheth et al. · Cell Systems · 2019 · 58 citations · Full text

Transcriptional Regulation, Systems Biology, Functional Genomics +10

Computational translation of genomic responses from experimental model systems to humans

Douglas K. Brubaker, Elizabeth A. Proctor, Kevin M. Haigis et al. · PLoS Computational Biology · 2019 · 50 citations · Full text

Engineering, Machine Learning, Genetics +26

Coagulopathy signature precedes and predicts severity of end‐organ heat stroke pathology in a mouse model

Elizabeth A. Proctor, Shauna M. Dineen, Stephen C. Van Nostrand et al. · Journal of Thrombosis and Haemostasis · 2020 · 46 citations · Full text

Thrombosis, End‐organ Heat, Hyperthermia +15