Concepedia

Toufike Kanouni

TK

14

Publications

810

Citations

12

H-Index

2010

Active since

Affiliations

German Marine Research Consortium(Current)

University of Freiburg

University Medical Center Freiburg

Deutschen Konsortium für Translationale Krebsforschung

Takeda (United States)

Toufike Kanouni is an author at German Marine Research Consortium specializing in medicine, drug discovery, and pharmacology.

Top concepts

MedicinePharmacologyDrug DiscoveryMedicinal ChemistryNatural SciencesRadiation OncologyOncologyBiochemistryCancer ResearchDrug Development

Publications per year

2010–2024

14

Publications

14

Discovery of TAK-733, a potent and selective MEK allosteric site inhibitor for the treatment of cancer

Qing Dong, Douglas R. Dougan, Xianchang Gong et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 120 citations · Full text

Medicine, Receptor Tyrosine Kinase, Anti-cancer Agent +6

Discovery of CC-90011: A Potent and Selective Reversible Inhibitor of Lysine Specific Demethylase 1 (LSD1)

Toufike Kanouni, Christophe Severin, Robert W. Cho et al. · Journal of Medicinal Chemistry · 2020 · 115 citations · Full text

KDM4 Inhibition Targets Breast Cancer Stem–like Cells

Eric Metzger, Stella S. Stepputtis, Juliane Strietz et al. · Cancer Research · 2017 · 109 citations · Full text

Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue

Delphine Duteil, Milica Tošić, Franziska Lausecker et al. · Cell Reports · 2016 · 90 citations · Full text

Obesity, Metabolic Syndrome, Adipose Tissue +13

Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models

Young K. Chen, Tiziana Bonaldi, Alessandro Cuomo et al. · ACS Medicinal Chemistry Letters · 2017 · 83 citations · Full text

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