Christophe Severin

Somatic Mutations Lead to an Oncogenic Deletion of Met in Lung Cancer

Monica Kong-Beltran, Somasekar Seshagiri, Jiping Zha et al. · Cancer Research · 2006 · 477 citations

Pathology, Oncogenic Deletion, Cancer Biology +18

Discovery of CC-90011: A Potent and Selective Reversible Inhibitor of Lysine Specific Demethylase 1 (LSD1)

Toufike Kanouni, Christophe Severin, Robert W. Cho et al. · Journal of Medicinal Chemistry · 2020 · 115 citations · Full text

Retinal axon growth cones respond to EphB extracellular domains as inhibitory axon guidance cues

Eric Birgbauer, Stephen F. Oster, Christophe Severin et al. · Development · 2001 · 79 citations

Ephb Extracellular Domains, Optic Nerve, Ventral Retina +16

GAP-43 mediates retinal axon interaction with lateral diencephalon cells during optic tract formation

Fan Zhang, Cynthia Lu, Christophe Severin et al. · Development · 2000 · 35 citations

Optic Tract Formation, Abstract Gap-43, Retinal Ganglion Cell +16

Structure-based design and discovery of potent and selective lysine-specific demethylase 1 (LSD1) inhibitors

Zhe Nie, Lihong Shi, Chon Lai et al. · Bioorganic & Medicinal Chemistry Letters · 2018 · 13 citations · Full text

Molecular Docking, Medicinal Chemistry, Drug Target +12