Linda P. O’Reilly

Medium-Chain Acyl-CoA Dehydrogenase (MCAD) Mutations Identified by MS/MS-Based Prospective Screening of Newborns Differ from Those Observed in Patients with Clinical Symptoms: Identification and Characterization of a New, Prevalent Mutation That Results in Mild MCAD Deficiency*

Brage Storstein Andresen, Steve F. Dobrowolski, Linda P. O’Reilly et al. · The American Journal of Human Genetics · 2001 · 232 citations · Full text

Clinical Symptoms, Mendelian Disorder, Prevalent Mutation +14

Fluphenazine Reduces Proteotoxicity in C. elegans and Mammalian Models of Alpha-1-Antitrypsin Deficiency

Jie Li, Stephen C. Pak, Linda P. O’Reilly et al. · PLoS ONE · 2014 · 50 citations · Full text

Cell Death, Alpha-1-antitrypsin Deficiency, Toxicological Mechanism +22

A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnover

Olivia S. Long, Joshua A. Benson, Joon Hyeok Kwak et al. · Human Molecular Genetics · 2014 · 46 citations · Full text

Protein Turnover, Molecular Biology, Human α1-Antitrypsin Deficiency +23

A genome-wide RNAi screen identifies potential drug targets in a C. elegans model of α1-antitrypsin deficiency

Linda P. O’Reilly, Olivia S. Long, Murat Can Çobanoğlu et al. · Human Molecular Genetics · 2014 · 44 citations · Full text

Tyrosine Phosphorylation in the SH3 Domain Disrupts Negative Regulatory Interactions within the c-Abl Kinase Core

Shugui Chen, Linda P. O’Reilly, Thomas E. Smithgall et al. · Journal of Molecular Biology · 2008 · 42 citations · Full text

Tyrosine Phosphorylation, Signal Transduction, C-abl Kinase Core +10