Olivia S. Long

Automated High-Content Live Animal Drug Screening Using C. elegans Expressing the Aggregation Prone Serpin α1-antitrypsin Z

Sager J. Gosai, Joon Hyeok Kwak, Cliff J. Luke et al. · PLoS ONE · 2010 · 177 citations · Full text

Drug Target, Engineering, Molecular Biology +16

An Intracellular Serpin Regulates Necrosis by Inhibiting the Induction and Sequelae of Lysosomal Injury

Cliff J. Luke, Stephen C. Pak, Yuko S. Askew et al. · Cell · 2007 · 169 citations · Full text

Inflammation, Protein Function, Disease Mechanism +14

A Pro-Cathepsin L Mutant Is a Luminal Substrate for Endoplasmic-Reticulum-Associated Degradation in C. elegans

Mark T. Miedel, Nathan J. Graf, Kate E. Stephen et al. · PLoS ONE · 2012 · 47 citations · Full text

Molecular Biology, Autophagy, Proteomics +22

A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnover

Olivia S. Long, Joshua A. Benson, Joon Hyeok Kwak et al. · Human Molecular Genetics · 2014 · 46 citations · Full text

Protein Turnover, Molecular Biology, Human α1-Antitrypsin Deficiency +23

A genome-wide RNAi screen identifies potential drug targets in a C. elegans model of α1-antitrypsin deficiency

Linda P. O’Reilly, Olivia S. Long, Murat Can Çobanoğlu et al. · Human Molecular Genetics · 2014 · 44 citations · Full text