Yuki Ohta

Modeling colorectal cancer using CRISPR-Cas9–mediated engineering of human intestinal organoids

Mami Matano, Shoichi Date, Mariko Shimokawa et al. · Nature Medicine · 2015 · 1.1K citations

Life Sciences, Biotechnology, Molecular Biology +16

A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis

Masayuki Fujii, Mariko Shimokawa, Shoichi Date et al. · Cell stem cell · 2016 · 853 citations · Full text

Medicine, Cancer Biology, Oncology +12

Visualization and targeting of LGR5+ human colon cancer stem cells

Mariko Shimokawa, Yuki Ohta, Shingo Nishikori et al. · Nature · 2017 · 749 citations

Medicine, Cell Biology, Oncology +10

Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression

Takashi Seino, Shintaro Kawasaki, Mariko Shimokawa et al. · Cell stem cell · 2018 · 638 citations

Medicine, Cell Biology, Oncology +14

Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesis

Shigeki Shimba, Norimasa Ishii, Yuki Ohta et al. · Proceedings of the National Academy of Sciences · 2005 · 529 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14