Joan Helmering

Pharmacologic Effects of FGF21 Are Independent of the “Browning” of White Adipose Tissue

Murielle M. Véniant, Glenn Sivits, Joan Helmering et al. · Cell Metabolism · 2015 · 194 citations

Metabolic Syndrome, Metabolic Disorder, Medicine +10

FGF21 Promotes Metabolic Homeostasis via White Adipose and Leptin in Mice

Murielle M. Véniant, Clarence Hale, Joan Helmering et al. · PLoS ONE · 2012 · 142 citations · Full text

Metabolic Disorder, Glucose Tolerance, Insulin Signaling +21

Chronic glucose-dependent insulinotropic polypeptide receptor (GIPR) agonism desensitizes adipocyte GIPR activity mimicking functional GIPR antagonism

Elizabeth A. Killion, Michelle Chen, James R. Falsey et al. · Nature Communications · 2020 · 129 citations · Full text

Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors

David J. Lloyd, David J. St. Jean, Robert J. Kurzeja et al. · Nature · 2013 · 96 citations

Biochemistry, Medicine, Insulin Management +6

Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 3. Structure–Activity Relationships within the Aryl Carbinol Region of the <i>N</i>-Arylsulfonamido-<i>N</i>′-arylpiperazine Series

Nobuko Nishimura, Mark H. Norman, Longbin Liu et al. · Journal of Medicinal Chemistry · 2014 · 52 citations · Full text

Molecular Biology, Chemical Biology, Structure–activity Relationships +22