Aravind Basavapathruni

Potent inhibition of DOT1L as treatment of MLL-fusion leukemia

Scott R. Daigle, Edward J. Olhava, Carly A. Therkelsen et al. · Blood · 2013 · 718 citations · Full text

Conformational Adaptation Drives Potent, Selective and Durable Inhibition of the Human Protein Methyltransferase DOT1L

Aravind Basavapathruni, Lei Jin, Scott R. Daigle et al. · Chemical Biology & Drug Design · 2012 · 141 citations · Full text

Computer-aided design of non-nucleoside inhibitors of HIV-1 reverse transcriptase

William L. Jorgensen, Juliana Ruiz‐Caro, Julian Tirado‐Rives et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 135 citations

Human Retrovirus, Hiv-1 Reverse Transcriptase, Molecular Biology +5

Impact of enzyme concentration and residence time on apparent activity recovery in jump dilution analysis

Robert A. Copeland, Aravind Basavapathruni, Mikel P. Moyer et al. · Analytical Biochemistry · 2011 · 110 citations

Apparent Activity Recovery, Engineering, Environmental Engineering +4

Probing the Molecular Mechanisms of AZT Drug Resistance Mediated by HIV-1 Reverse Transcriptase Using a Transient Kinetic Analysis

Adrian S. Ray, Eisuke Murakami, Aravind Basavapathruni et al. · Biochemistry · 2003 · 77 citations