Mandy Beswick

Structure-Activity Relationships in Purine-Based Inhibitor Binding to HSP90 Isoforms

Lisa Wright, Xavier Barril, Brian Dymock et al. · Chemistry & Biology · 2004 · 268 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

4-Amino derivatives of the Hsp90 inhibitor CCT018159

Xavier Barril, Mandy Beswick, Adam J. Collier et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 80 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

3-(5-chloro-2,4-dihydroxyphenyl)-Pyrazole-4-carboxamides as inhibitors of the Hsp90 molecular chaperone

Paul A. Brough, Xavier Barril, Mandy Beswick et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 80 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +10

Adenine derived inhibitors of the molecular chaperone HSP90—SAR explained through multiple X-ray structures

Brian Dymock, Xavier Barril, Mandy Beswick et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 64 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +13

Discovery of C-(1-aryl-cyclohexyl)-methylamines as selective, orally available inhibitors of dipeptidyl peptidase IV

Kenji Namoto, Finton Sirockin, Nils Ostermann et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 19 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8