Lisa Sevenich

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

Stephanie M. Pyonteck, Leila Akkari, Alberto J. Schuhmacher et al. · Nature Medicine · 2013 · 2.5K citations · Full text

Life Sciences, Neuroscience, Oncology +12

Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies

Robert L. Bowman, Florian Klemm, Leila Akkari et al. · Cell Reports · 2016 · 627 citations · Full text

Life Sciences, Cell Biology, Oncology +13

Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S

Lisa Sevenich, Robert L. Bowman, Steven D. Mason et al. · Nature Cell Biology · 2014 · 377 citations · Full text

Medicine, Cancer Biology, Oncology +16

Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice

Lisa Sevenich, Uta Schurigt, Kathrin Sachse et al. · Proceedings of the National Academy of Sciences · 2010 · 177 citations · Full text

Medicine, Cancer Biology, Oncology +13

Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix

Leila Akkari, Vasilena Gocheva, Jemila C. Kester et al. · Genes & Development · 2014 · 120 citations · Full text

Medicine, Cancer Biology, Oncology +17