Nian Tong

Folate transporter dynamics and therapy with classic and tumor-targeted antifolates

Carrie O’Connor, Adrianne Wallace-Povirk, Changwen Ning et al. · Scientific Reports · 2021 · 33 citations · Full text

Medicine, Oncology, Pharmacology +13

Fluorine-Substituted Pyrrolo[2,3-<i>d</i>]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of<i>de Novo</i>Purine Nucleotide Biosynthesis

Manasa Ravindra, Mike R. Wilson, Nian Tong et al. · Journal of Medicinal Chemistry · 2018 · 27 citations · Full text

Medicine, Oncology, Pharmacology +13

A Pilot Study To Assess the Suitability of Riboflavin As a Surrogate Marker of Breast Cancer Resistance Protein in Healthy Participants

Hong Shen, Runlan Huo, Yueping Zhang et al. · Journal of Pharmacology and Experimental Therapeutics · 2024 · 15 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +13

Discovery of 6-substituted thieno[2,3-d]pyrimidine analogs as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis in folate receptor expressing human tumors

Adrianne Wallace-Povirk, Nian Tong, Jennifer Wong-Roushar et al. · Bioorganic & Medicinal Chemistry · 2021 · 12 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Medium optimization and subsequent fermentative regulation enabled the scaled‐up production of anti‐tuberculosis drug leads ilamycin‐E1/E2

Zhiying Fan, Nian Tong, Zhoukang Zhuang et al. · Biotechnology Journal · 2022 · 12 citations

Life Sciences, Biotechnology, Microbiology +17